Wound, Ostomy and Continence Nurses Society (WOCN) Practice Exam

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What corticosteroid dose is a concern regarding its impact on wound healing?

10mg/day
20mg/day
30mg/day
40mg/day or more

The correct answer is: 40mg/day or more

Corticosteroids are known to impact various physiological processes, including wound healing. When considering the specific dosing of corticosteroids, higher doses are generally associated with more significant effects on the body's inflammatory response. A dose of 40mg/day or more is particularly concerning because it can suppress the immune system, reduce collagen synthesis, and impair wound healing mechanisms. At these elevated levels, the anti-inflammatory effects of corticosteroids can hinder the normal inflammatory phase of wound healing, which is crucial for the formation of granulation tissue and eventual healing of the wound. Lower doses, such as 10mg, 20mg, or 30mg per day, may still have some effect on healing, but the potential for severe impairment becomes markedly greater at and above the 40mg threshold. This understanding is essential for practitioners in the field to recognize the implications of corticosteroid therapy on patients with wounds, ensuring that they monitor and manage these therapies according to their impact on healing.